School of Medicine - Medicine

  • Professor
  • BAEK, KWAN HYUCK 홈페이지 바로가기
    Lab Tumor microenvironment laboratory
CV1

Education

  • 3/1997 ~ 2/2002. Ph.D., Cellular Immunology, Pohang University of Science and Technology, Korea. (Advisor: Dr. Young Chul Sung)
  • 3/1994 ~ 2/1997. M.Sc., Viral Immunology, Pohang University of Science and Technology, Korea. (Advisor: Dr. Young Chul Sung)
  • 3/1990 ~ 2/1994. B.Sc., Life Science, Pohang University of Science and Technology, Korea.

Experience

  • 4/2020 ~ Present. Professor, Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine
  • 4/2014 ~ 3/2020. Associate Professor, Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine
  • 3/2010 ~ 3/2014. Assistant Professor, Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine
  • 6/2009 ~ 2/2010. Postdoctoral Fellow, Dept. of Cancer Biology, Abramson Family Cancer Research Institute, University of Pennsylvania, School of Medicine. (Principal Investigator: Dr. Sandra Ryeom)
  • 5/2006 ~ 6/2009. Research fellow, Vascular Biology Program, Department of Surgery, Children’s Hospital, Boston, Harvard Medical School. (Principal Investigator: Dr. Sandra W. Ryeom / Dr. Judah Folkman)
  • 1/2006 ~ 4/2006. Postdoctoral fellow, SamSung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Korea (Principal Investigator: Dr. Chang Woo Lee)
  • 7/2003 ~ 12/2005. Postdoctoral fellow, Research Institute, National Cancer Center, Korea (Principal Investigator: Dr. Chang Woo Lee)
  • 3/2002 ~ 6/2003. Postdoctoral fellow, Pohang University of Science and Technology, korea (Principal Investigator: Dr. Young Chul Sung)

Journal Articles

  • (2024)  S6K1 deficiency in tumor stroma impairs lung metastasis of melanoma in mice.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.  696, 
  • (2021)  Bioactivity-based analysis and chemical characterization of cytotoxic compounds from a poisonous mushroom, Amanita spissacea, in human lung cancer cells in vitro.  NATURAL PRODUCT RESEARCH.  35,  4
  • (2020)  Loss of S6K1 But Not S6K2 in the Tumor Microenvironment Suppresses Tumor Growth by Attenuating Tumor Angiogenesis.  TRANSLATIONAL ONCOLOGY.  13,  4
  • (2019)  A single extra copy of Down syndrome critical region 1-4 results in impaired hepatic glucose homeostasis.  MOLECULAR METABOLISM.  21,  1
  • (2019)  Extracellular cyclic adenosine monophosphate-dependent protein kinase A autoantibody and C-reactive protein as serum biomarkers for diagnosis of cancer in dogs.  VETERINARY AND COMPARATIVE ONCOLOGY.  17,  1
  • (2018)  Testicular endothelial cells are a critical population in the germline stem cell niche.  NATURE COMMUNICATIONS.  9,  1
  • (2018)  Bioactivity-based analysis and chemical characterization of cytotoxic constituents from Chaga mushroom (Inonotus obliquus) that induce apoptosis in human lung adenocarcinoma cells.  JOURNAL OF ETHNOPHARMACOLOGY.  224, 
  • (2018)  Bioactivity-guided isolation of ginsenosides from Korean Red Ginseng with cytotoxic activity against human lung adenocarcinoma cells.  JOURNAL OF GINSENG RESEARCH.  42,  4
  • (2018)  Differential impact of circulating tumor cells on disease recurrence and survivals in patients with head and neck squamous cell carcinomas: An updated meta-analysis.  PLOS ONE.  13,  9
  • (2018)  Cytotoxic Constituents from the Sclerotia of Poria cocos against Human Lung Adenocarcinoma Cells by Inducing Mitochondrial Apoptosis.  CELLS.  7,  9
  • (2018)  Bioactivity evaluations of betulin identified from the bark of Betula platyphylla var. japonica for cancer therapy.  ARCHIVES OF PHARMACAL RESEARCH.  41,  8
  • (2018)  Treatment outcomes in metastatic and localized high-grade salivary gland cancer: high chance of cure with surgery and post-operative radiation in T1-2 N0 high-grade salivary gland cancer.  BMC CANCER.  18, 
  • (2018)  Bioactivity-guided isolation and chemical characterization of antiproliferative constituents from morel mushroom (Morchella esculenta) in human lung adenocarcinoma cells.  JOURNAL OF FUNCTIONAL FOODS.  40, 
  • (2018)  Postoperative anti-PD-1 antibody treatment to reduce recurrence in a cancer ablation surgical wound.  JOURNAL OF SURGICAL RESEARCH.  221, 
  • (2017)  Vulpinic acid contributes to the cytotoxicity of Pulveroboletus ravenelii to human cancer cells by inducing apoptosis.  RSC ADVANCES.  7,  56
  • (2017)  Discrepancy between cTNM and pTNM staging of oral cavity cancers and its prognostic significance.  JOURNAL OF SURGICAL ONCOLOGY.  115,  8
  • (2017)  Antiproliferative effect of Momordica cochinchinensis seeds on human lung cancer cells and isolation of the major constituents.  REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY.  27,  3
  • (2017)  Pinecone of Pinus koraiensis Inducing Apoptosis in Human Lung Cancer Cells by Activating Caspase-3 and its Chemical Constituents.  CHEMISTRY BIODIVERSITY.  14,  4
  • (2017)  A novel cytotoxic activity of the fruit of Sorbus commixta against human lung cancer cells and isolation of the major constituents.  JOURNAL OF FUNCTIONAL FOODS.  30, 
  • (2017)  Characteristics of extracellular cyclic AMP-dependent protein kinase as a biomarker of cancer in dogs.  VETERINARY AND COMPARATIVE ONCOLOGY.  15,  4